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2011年9月15日星期四

Bob Kahrs: Infectious bovine rhinotracheitis

Infectious bovine rhinotracheitis (IBR) is caused by Bovine Herpes Virus-1. It is a globally distributed respiratory infection of cattle that induces fever, loss of appetite, coughing, rapid breathing, and nasal discharge. It can cause pregnant cattle to abort within 100 days of infection.

It sometimes produces diagnostically significant pus-filled cold-sore-like lesions in the nasal passages. These are found with flashlight-assisted searches and are often overlooked.

Initial IBR infections are usually non-fatal but can become deadly when complicated by stress, secondary bacterial infections including pneumonia, bovine virus diarrhea (BVD) virus, parainfluenza-3 virus, or other infections.

A closely related strain of Bovine herpesvirus-1 is called infectious pustular vulvovaginitis (IPV) virus. IPV virus causes cold-sore-like lesions in the birth canal and on male genitals. IBR and IPV differ largely by their method of transmission and the fact that IPV is usually a localized infection.

Both of these bovine herpesviruses produce persistent latent infections that are carried for years and can be reactivated in healthy cows by stress or steroid injections. Such carrier cattle can initiate outbreaks in susceptible herds that are unvaccinated and free of infection.

IBR is diagnosed by its clinical signs and lesions, by isolation of the virus, or by paired blood samples that lack IBR antibodies early in the infection but are positive three weeks later. Treatment with antibacterials helps control secondary infections.

2011年8月9日星期二

Who’s the Heroine of The Help?

If you haven’t already read The Help, chances are you know someone in a book club who has. Kathryn Stockett’s novel about white women and their black maids in 1960s Jackson, Miss. has been a massive bestseller since its release in February 2009 and continues to sit pretty at the top of the charts.

But as widely beloved as the novel has been, it’s also been shadowed by controversy. After all, The Help is a book written by a white woman, in which a young, privileged white woman empowers and elevates a town’s black population by getting a book published about their experiences. The black characters’ thick dialect raised some eyebrows (“I reckon that’s the risk you run, letting somebody else raise you chilluns”), and a lawsuit filed by an African-American nanny and housekeeper who claims Stockett appropriated her identity exacerbated the book’s already “squicky” racial politics, as Salon’s Laura Miller called them.

Audiences will have another opportunity to appraise Stockett’s Jackson when the film adaptation of The Help, directed by Tate Taylor, opens in theaters tomorrow. The movie is getting a push from many African-American groups and community leaders, including the chairwoman of the NAACP, who tout the film as a rare example of a high-profile, mainstream entertainment starring strong black women. If the screening I saw last week is any indication, the brightly colored drama is guaranteed to be an audience pleaser, and it comes with an unimpeachable moral message: It’s bad to be a racist. But critics are asking: Just how progressive is it?

One of the key questions is to what extent the film represents Skeeter Phelan—the young Junior  League member who is one of the novel’s three narrators, along with maids Aibileen and Minny—as some kind of savior of the women whose experiences she documents in her book. Several critics have grouped the movie with films like Mississippi Burning, To Kill a Mockingbird, and The Blind Side, which see “racial progress as the province of white do-gooderism,” as Wesley Morris wrote today in the Boston Globe.

Unavoidably, the film flattens out some of the nuance of the 464-page book. In the novel, Stockett (perhaps hoping to sidestep accusations of Mary Sue-ism) complicates the notion that Skeeter is the story’s heroine by making it clear that Skeeter’s personal career ambitions, as much as—if not more than—her social conscience are what push her to interview her friends and neighbors’ domestic employees. In the film, however, the moral lines are much more brightly drawn. In the novel, Skeeter’s sense of injustice on behalf of Jackson’s maids takes time to kindle, but here her crusading sensibility is established right off the bat. (We know she’s an unconventional thinker because she has wild, curly hair, unlike her peers, with their Stepford bouffants.) The villain Hilly Holbrook, as played by Bryce Dallas Howard, practically glows with cartoonish evil. (We know she’s rotten inside because she gets cold sores.) A character who, in the novel, is both a fine person and a racist—and allowed to inhabit both of those seemingly contradictory roles—gets an over-the-top redemption in the movie. It’s enjoyable, as melodrama can be, and undeniably powerful, but the film doesn’t always capture the “nuanced humanity” that filmmaker and author Nelson George calls for in a New York Times essay about Hollywood depictions of civil rights struggles.